Electrospray from nanostructured tungsten oxide surfaces with ultralow sample vo

2019-09-15 21:34:36

solution tungsten oxide ton electrospray

责任者: Jeng, Jingyueh;Lin, Che-Hsin;Shiea, Jentaie 单位: Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, Taiwan 来源出处: Analytical Chemistry,2005,77(24):8170-8173 摘要: This study demonstrated the feasibility of performing protein analysis with ultralow sample volume by combining a tungsten oxide nanowire (TON) fiber with a miniaturized electrospray ionization interface. An increase in wettability of the tugsten surface after growing randomly oriented TON on its surface allows strong adhesion of [similar to] 50 nL of the methanol solution at its tip. Under the influence of a high electric field, electrospray from a Taylor cone on the adhered methanol solution was observed and the multiply charged ions of protein molecules predissolved in the solution were detected. © 2005 American Chemical Society. 关键词: Spraying;Electrochemistry;Tungsten compounds;Nanostructured materials;Surface structure;Ionization;Adhesion;Methanol;Electric fields;Proteins;Electrospray;Tungsten oxide;Electrospray ionization interface;Protein molecules